Protein name:
Caspase-3 (CASP-3) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit.
Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MENTENSVDS | KSIKTSETKI | LHGSKSMDSG | ISLEESYKMD | YPEMGLCIII |
100:
NNKNFHENTG | MACRSGTDVD | AANLRETFMN | LKYEVRIKND | LTCKEMLELM |
150:
SNVSKEDHSK | RSSFICVLLS | HGEEGIIFGT | NGPVNLKKLA | SFFRGDYCRS |
200:
LTGKPKLFII | QACRGTELDC | GIETDSGAED | DMACQKIPVE | ADFLYAYSTA |
250:
PGYFSWRNAK | NGSWFIQALC | EMLKKHAHRL | ELMHILTRVN | RKVAIEYESF |
275:
STDSAFHAKK | QIPCIMSMLT | KELYF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
Rat
Pig
Rabbit
Dog
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
ELISA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
CLIA Kit for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Polyclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Monoclonal Antibody for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
Protein for Bovine CASP-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Brain cortex .